Antifungal activity of essential oil of Amyrisbalsamifera against Cryptococcusneoformans
نویسندگان
چکیده
Background Cryptococcus neoformans can cause infection in immunocompromissed individuals, especially in patients with acquired immunodeficiency syndrome, in which meningoencephalitis is the main clinical manifestation [1]. There are few available antifungals for cryptococcosis treatment and all of them present high toxicity, besides the reports of resistance. In this context, the natural products from plants are an important source in the search for new antifungal compounds. In this study, it was evaluated the antifungal activity of the Amyrisbalsamifera essential oil (EO) against C. neoformans. The determination was made by minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) using the microdilution broth method.
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